When we evaluated the presence of SDHD in cervical cancer biopsies, the SDH subunit with strongest reduction in expression mediated by Th17 cells, we found a heterogeneous expression of SDHD within the biopsies and diminished expression of SDHD correlated with advanced tumor FIGO stages, lymph node metastases and cervical cancer recurrence. Here, SDHD is linked to neoplasm.