The mRNA expression levels of SF3B4 and other MDSC markers in HCC tissues of the same patient showed a high positive correlation (Pearson’s r = 0.64 for ITGAM, Pearson’s r = 0.57 for S100A9, Pearson’s r = 0.61 for CD80, and Pearson’s r = 0.70 for CD83), except for LOX (Fig. 6F). Here, ITGAM is linked to hepatocellular carcinoma.