SF3B4 and hepatocellular carcinoma: We performed survival analyses to further investigate the association between the prognoses of patients with HCC and the expression of SF3B4. Patients with high SF3B4 expression had worse OS, DFS, DSS, and PFS (OS, log-rank P < 0.0001, hazard ratio [HR] = 2.04; DFS, log-rank P = 0.04, HR = 1.39; DSS, log-rank P = 0.008, HR = 1.82; PFS, log-rank P = 0.042, HR = 1.36; Fig. 1B).