In our study, we found that T2, ADC, FA, and IMAT (%) values correlated positively with key clinical indicators (fasting blood glucose, fasting insulin, OGTT-AUC, and HOMA-IR) in IMAT and muscles, indicating that multimodal MRI can help detect metabolic changes in IMATs in prediabetes subjects. The gene discussed is INS; the disease is prediabetes syndrome.