CDH16 and differentiated thyroid carcinoma: In a recent study conducted by Lennartz et al.22, which analyzed over 10,000 tumors spanning more than 100 entities, CDH16 positivity was identified in 100% of normal thyroid tissues, 86% of 94 follicular adenomas, 60% of 67 follicular carcinomas and only 6.6% of 212 papillary thyroid carcinomas.