As shown in Table 2, PCMT1 protein expression was closely related to Gleason score, clinical stage, lymph node metastasis and bone metastasis (P = 0.003, 0.003, 0.036, 0.020, respectively) of patients with PCa, but was not associated with age (P = 0.053) and preoperative prostate specific antigen (PSA) (P = 0.679). This evidence concerns the gene PCMT1 and bone metastasis.