This corresponded with increased CD3+ and CD8+ T-cell numbers in KPC3-TRP1 tumors, as determined by the proportion of CD3-stained or CD8-stained tumor area, which was most pronounced at 72 hours pi (figure 5B,C, KPC3 vs KPC3-TRP1: 0.11±0.02 vs 5.45±0.95% CD3-DAB-stained area, p<0.01). The gene discussed is TYRP1; the disease is neoplasm.