Currently neither SCCPDH or STAM2 have been directly linked with IR/T2D although STAM2 has been shown to be modulated by maternal diabetes in the developing embryo in an animal experimental model [42] suggesting a role for STAM2 in T1D and as a target for perturbations induced by maternal diabetes and transgenerational inheritance of phenotype. The gene discussed is STAM2; the disease is type 1 diabetes mellitus.