A variety of myositis-specific antibodies (MSAs) had been identified for phenotyping of DM and early recognition of high risk patients, such as the most prevalent anti-Jo-1 (occurring in 9–24% of adult DM patients [3]), anti-melanoma differentiation-associated gene 5 (anti-MDA5, occurring from 15 to 20% in Asian DM patients [4]), and less common anti-PL-7, anti-EJ, anti-PL-12, anti-OJ, et al. [5, 6]. This evidence concerns the gene IFIH1 and myositis disease.