C5 and acute myeloid leukemia: By Using the c5 gene set, we found that AML patients with high-risk phenotypes were notably enriched in the T cell apoptotic process, TNF pathway, NF/kappa B, cell–cell adhesion, MAPK pathway, TCR, T cell-mediated immunity, B cell activation involved in the immune response, and TLR signaling pathway (Fig. 8A–P, Table S7).