Through network pharmacological research, 6 key targets including IL6, VEGFA, JUN, TP53, 1L1B and PTGS2 were screened as important anti-PTC targets of SS. Through the construction of SS “drug-component-disease” target network and target gene PPI network, it was revealed that the target sites coordinated the process of proliferation, apoptosis, differentiation and metabolism to inhibit tumor metastasis through interaction. The gene discussed is TP53; the disease is neoplasm.