To determine whether active viral infection was responsible for the observed induction of antiviral and inflammatory genes, or whether gene expression was induced by unspecific activation of pattern recognition receptors, we also treated the JFB organoids with a panel of TLR agonists targeting TLR2, 3, 7, and 9 and with UV-inactivated SARS-CoV-2 for 48 h. The gene discussed is TLR2; the disease is viral infectious disease.