FL and DLBCL showed multiple mutations in the same patient of KMTD (n = 101), CREBBP (n = 39), and HIST1H1E (n = 20), in addition to aberrant somatic hypermutation of BCL2 (n = 58), PIM1 (n = 41), and SOCS1 (n = 22). This evidence concerns the gene SOCS1 and diffuse large B-cell lymphoma.