In this analysis we identified a total of 54 germline variants from myeloid neoplasms in genes associated with response to HMA treatment that could have been misattributed to being of somatic origin without a matched normal sample: TET2 (n = 47), DNMT3A (n = 4), and TP53 (n = 3) (Supplementary Table 3). This evidence concerns the gene TP53 and myeloid neoplasm.