Consistent with a role for IL13 and IL25 in establishing a tumor promoting feed-forward circuit involving tuft cells and ILC2s, tumors from antibody-treated mice showed reduced proportions of tuft cells (Fig. 5e, f) and iILC2s (Fig. 5g, h), as well as diminished expression of the corresponding cell type-specific genes Dclk1/Il25 and Gata3/Il13 (Supplementary Fig. 5g, h). This evidence concerns the gene DCLK1 and neoplasm.