EPCAM and adenoma: Indeed, when compared to the mucosa of wild-type gp130+/+ mice, we detected increased proportions of DCLK1+ and SiglecF+CD24+EpCAM+ tuft cells in the adenomas of gp130F/F mice (Supplementary Fig. 3c, d), which coincided with an increased abundance of iILC2s, but not nILC2s (Supplementary Fig. 3e-g).