IL5 and gastric cancer: To explore the contribution of tuft cells and ILC2s to the formation of SPEM-independent sporadic gastric cancer, we utilised the N-Methyl-N-Nitrosourea (MNU) model57, and administered this carcinogen to ILC2-deficient R5-IL5;dtTomato-IRES-CreLSL-Rosa26DTA mice (referred to as TC;WTILC2Δ mice58) or compound mutant mice to achieve simultaneous ablation of ILC2 and tuft cell (TC;ΔILC2Δ) (Fig. 2i).