One of them (NCT03017820) shows complete remissions with a recombinant VSV expressing IFNβ (for conferring specificity and enhancing the anti-tumor response) and a sodium iodide symporter (NIS), for allowing uptake of radiotracers, exhibiting potent viral replication, along with an increase in tumor-reactive T cells [127]. The gene discussed is IFNB1; the disease is neoplasm.