However, Zhang et al. used different methods to identify insulin-like growth factor 2 MRNA binding protein 2 (IGF2BP2) and matrix metallopeptidase 9 (MMP-9) as potential antigens for developing mRNA vaccines against bladder cancer when analyzing 404 primary bladder cancer tissue samples across four stages I-IV [36]. The gene discussed is IGF2BP2; the disease is urinary bladder carcinoma.