MTOR and early-onset autosomal dominant Alzheimer disease: Regarding KEGG analysis, the top 15 enriched pathways were mainly the Cell cycle, Protein processing in endoplasmic reticulum, Proteasome, Parkinson disease, Alzheimer disease, Oxidative phosphorylation, Thermogenesis, Huntington disease, Non-alcoholic fatty liver disease (NAFLD), Spliceosome, Metabolic pathways, mTOR signaling pathway, B cell receptor signaling pathway, Th17 cell differentiation, and T cell receptor signaling pathway (Figure 3E).