ACE2 and COVID-19: At the same time, a comparison of healthy boys and boys with COVID-19 showed a significant difference in ACE2 rs2074192 genotype frequencies (χ2 = 6.94; p = 0.031); healthy children and those infected with SARS-CoV-2 girls did not differ in terms of genotype frequency (χ2 = 0.68; p = 0.711) (Table 5).