For example, 48 h after infection, the transcription levels of OASL, Mx, MDA5, and MAVS were upregulated in the FAdV-4 GY single-infected group (group A) and the group subjected first to FAdV-4 GY infection with aHEV-YT and then infection with aHEV-YT (group C) after culturing with LMH cells. The gene discussed is MAVS; the disease is infection.