As shown in Figure 8, after 48 h of infection, LMH cells infected with FAdV-4 GY (group A) showed significant upregulation of the transcription levels of most immuno-cytokines (IL18, TLR7, IFN-α, and IFN-β excepted), such as OASL, Mx, MDA5, and MAVS. Here, IFIH1 is linked to infection.