With the caveat that NDFIP2 is very likely to control the levels of different proteins in addition to IFITM3, the fact that the removal of NDFIP2 leads to a decrease in IFITM3 levels and that it concomitantly exposes the cell to infection is compelling and in line with the broad antiviral role of IFITMs. This evidence concerns the gene IFITM3 and infection.