Despite its hepatotoxic effects at doses exceeding 10 mg/kg, it is worth highlighting that many of TSN’s beneficial properties, including its anti-cancer [36], anti-obesity [32], anti-viral [31], and anti-colitis effects [32], have been observed at significantly lower doses ranging from 0.1 to 1 mg/kg/day, without causing toxicity in major organs, including the liver. This evidence concerns the gene TSN and obesity due to melanocortin 4 receptor deficiency.