I.P. injection of SSHT also rescued the renal failure of C3H/He and (BALB/c × DBA/2) F~(CDF) female mice [79] and showed significant anti-inflammatory activity at a low dose of 100 mg/mouse by increasing granulocyte macrophage colony-stimulating factor (GM-CSF) secretion [80]. The gene discussed is CSF2; the disease is acute kidney injury.