CXCR4 and colonic neoplasm: Similarly, miR-663a has demonstrated upregulated expression across diverse cancer types, such as nasopharyngeal carcinoma, lung cancer, and colon cancer, reflecting its versatile functions in distinct biological contexts and its modulation of pivotal genes, such as p21, TGF-β1, and CXCR4-p21 [42,43,44].