Similarly, miR-663a has demonstrated upregulated expression across diverse cancer types, such as nasopharyngeal carcinoma, lung cancer, and colon cancer, reflecting its versatile functions in distinct biological contexts and its modulation of pivotal genes, such as p21, TGF-β1, and CXCR4-p21 [42,43,44]. This evidence concerns the gene CXCR4 and malignant colon neoplasm.