PVT1 and posterior cortical atrophy: Although the precise pathogenesis and underlying mechanisms of endothelial-to-mesenchymal transition in PCa remain elusive, Chang and Song have provided evidence that Plasmacytoma Variant Translocation 1 (PVT1), a newly identified long non-coding RNA, plays an instrumental role in promoting PCa invasion and metastasis by modulating endothelial–mesenchymal transition [98].