The GO enrichment analysis suggested that these genes were mainly related to “immune response-activating cell surface receptor signaling pathway”, “humoral immune response”, “lymphocyte mediated immunity”, “adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains”, “immunoglobin complex”, and “antigen binding”, strongly indicating its key role in tumor immunity in the microenvironment. This evidence concerns the gene CD177 and neoplasm.