Previous reports have identified two variants in the olfactory receptor region associated with various phenotypes: rs7948471-A in OR51B5 associated with a higher degree of hemolysis in SCD (p = 3 × 10−10), rs5006884-A in OR51B5 associated with an increased HbF level (p = 3 × 10−8) [72], and rs7950726-A in OR51V1 associated with variable HbA2 levels in healthy adults (p = 1 × 10−11) [73]. This evidence concerns the gene OR51V1 and Schnyder corneal dystrophy.