HBG1 and thalassemia: The variant rs2071348 was previously reported as a predictor for disease severity in anemic patients with β0-thalassemia/hemoglobin E (p = 3 × 10−15, OR = 4.05) [80], whereas a strong association between HBG1 (rs998870472) and low hemoglobin levels was recently reported (p = 1 × 10−273) [81].