Other genetic alterations are related to the development of NSCLC, such as changes in anaplastic lymphoma kinase (ALK), ROS 1 (ROS proto-oncogene 1), MET (mesenchymal-epithelial transition factor), RET (RET proto-oncogene), NTRK 1-3 (neurotrophic tyrosine kinase type 1–3), and HER2 (human epidermal growth factor receptor 2) genes. The gene discussed is RET; the disease is non-small cell lung carcinoma.