The most prevalent EGFR mutations found in NSCLC are the following: exon 19 deletions (45%); exon 21 L858R point mutation (40%); exon 19 insertions, such as S768I, L861Q, G719X (in up to 10% of cases), and, rarely, exon 20 insertions (approximately 5% of cases) [65,66,67]. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.