We found that 4 (out of 6) BCP-ALLs showed strong NF-κB activity (ΔNF-κB > 10) in response to TNF-α, whereas 3 (out of 6) T-ALLs and 1 BCP-ALL presented an intermediate response (5 < ΔNF-κB < 8) and 3 T-ALLs and 1 BCP-ALL had a weak response (ΔNF-κB < 3) to TNF-α stimulation (Figure 3b). This evidence concerns the gene NFKB1 and acute lymphoblastic leukemia.