MTF2 and acute myeloid leukemia: In the AML samples with low MTF2, we identified genes dysregulated in processes such as the cell cycle, regulation of the RNA metabolic process, nuclear transport, the apoptotic process, histone modification, and the DNA damage response processes (DDR) (Figure 6A), in agreement with the biological processes we detected in our local MTF2-deficient AML cohort [13].