In total, 10 of the top 20 pathways were related to diseases that mostly involve tumor formation, including cell adhesion molecules, Th1 and Th2 cell differentiation, the chemokine signaling pathway, the B cell receptor signaling pathway, the tumor necrosis factor signaling pathway, the NF−kappa B signaling pathway, and the retinol signaling pathway. Here, TNF is linked to neoplasm.