Another systematic review and meta-analysis conducted by Wang M. et al. showed how vitamin D supplementation in a population of women with GDM can statistically significantly reduce serum FPG, insulin, and HOMA-IR, as well as complications related to childbirth (cesarean section, maternal hospitalization, and postpartum hemorrhage) and newborns (hyperbilirubinemia, giant children, hypoglycemia, polyhydramnios, fetal distress, and premature delivery). This evidence concerns the gene INS and gestational diabetes.