ANGPT1 and hydrops fetalis: The authors concluded that Ang 1–7 exerts beneficial renal and cardiac influences in rats with HF leading to the postulation that the ACE2/Ang 1–7 axis represents a compensatory reaction to the overactivity of ACE/AngII/AT1R system characterizing HF and indicating that Ang 1–7 may be a possible therapeutic modality in this situation.