When the tumor volume reached 1.5 cm3 in group 2 (TC-1), all mice were euthanized, and tumors were dissected and photographed, except the tumors in group 9 (TC-1 + Ad-E7 + PD-1) and group 10 (TC-1 + Ad-E7 + PD-L1), which had disappeared (Figure 2D). The gene discussed is PDCD1; the disease is neoplasm.