It is no surprise since Piezo2 channelopathy is suggested to attract more neuro-energetic resources in the affected spinal segment as a compensatory and protective mechanism, e.g., in the form of exaggerated contractions, but as a consequence, the highest spinal neuro-energetic proprioceptive capacity, namely the cervical region, will be negatively affected due to resource limitations of the overall proprioceptive system [3,16,20] or even more precisely the Piezo system [10]. Here, PIEZO2 is linked to channelopathy.