In contrast to AML LSCs, CML LSCs can display a characteristic expression profile including CD25 (interleukin-2 receptor alpha chain), CD26 (dipeptidyl peptidase-4), or IL1-RAP (interleukin-1 receptor accessory protein) [44]. This evidence concerns the gene LRPAP1 and chronic myelogenous leukemia, BCR-ABL1 positive.