TRPC6 and type 2 diabetes mellitus: Resveratrol, an indirect positive modulator of TRPC6 activity [88], attenuates behavioral impairment in rats with type 2 diabetes mellitus (T2DM) induced by a high-fat diet and streptozotocin in the novel object recognition test, elevated plus maze test, light–dark passive avoidance tests, radial arm maze and nest building behavior study [100].