MYH7 and heart failure: Cardiomyopathy-related genes such as B-type natriuretic peptide (nppb) [21], encoding the BNP protein, an indicator of heart failure, and myosin heavy chain 7 (Myh7) [22], encoding the beta (slow) heavy chain subunit of cardiac myosin, were both altered in db/db mice compared with WT mice.