MYC and neoplasm: The links between oncogenic molecular tumor pathways (e.g., MYC) and genes regulating lactate metabolism (e.g., LDH) emerged [11], and it has now become clear that lactate plays a role as a metabolic substrate, a signaling molecule, and it has a leading role in a metabolic crosstalk between cancer cells and tumor microenvironment (TME) [12,13].