IL6 and Large vessel vasculitis: Although the role of IL-6 in the pathogenesis of large vessel vasculitis is well-defined [22], its possible impact on AAV development and progression is not as well elucidated, but Monach et al. in a relatively new paper indicated that the serum of patients with an active stage of AAV is characterised by a higher concentration of IL-6 than in the serum of patients with an inactive phase [14].