Importantly, over ten single nucleotide polymorphisms (SNPs, including G-395 A/rs1207568, F352 V/rs9536314, and C1818 T/rs564481) have been identified in the human KL gene, and their significant association with the etiology or treatment of many diseases (e.g., neurological and cancer) has been confirmed [56,57]. Here, KL is linked to cancer.