In a mouse T2DM-associated NAFLD model, BM-MSC transplantation reversed the abnormally elevated alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglycerides (TGs), and total cholesterol levels; completely reversed steatosis; and restored to normalcy, such hepatocyte mitochondria characteristic morphology, mtDNA copy number, oxygen consumption rate, and ATP production. Here, GPT is linked to steatosis.