Q also induces apoptosis and cell cycle arrest via c-JUN NH2-terminal kinase/nuclear transcription factor-kappa B/Akt (JNK/NF-kB/Akt) signal pathway inhibition and upregulating the expression of Bcl-2-associated X protein (Bax), cleaved caspase-3, cyclin B1, p21/53 proteins, and downregulating the B-cell lymphoma-2 (Bcl-2) cascade mediated by EGFR in NSCLC cells [19,20,21,22]. Here, CASP3 is linked to non-small cell lung carcinoma.