CHRNA7 and non-small cell lung carcinoma: Quercetin (Q) and its glycoside isoquercitrin (IQ) and rutin (RU) are natural flavonols found mostly in fruits, and are considered as positive allosteric modulators (PAMs)/selective agonists of human α7nAChR, which makes them potential therapeutic agents in nicotine-induced NSCLC [16,17].