In addition to serving as a target for molecular imaging, the significant difference in the GLP-1R expression between non-metastatic and metastatic insulinomas suggests that the immunohistochemical GLP-1R expression may prove to be, upon follow-up validation, a beneficial prognostic factor in estimating the metastatic potential of the tumours and thus the prognosis of surgically treated patients with insulinoma. Here, GLP1R is linked to pancreatic insulinoma.