To date, a number of biomarkers with a diagnostic value for each B-cell lymphoma subtype have been determined: BCL2, BCL6, CD10, CD21, and STMN1 in FL; D1 and SOX11 in MCL; FOXP1 and MUM1 in ABC-DLBCL; CD10, BCL2, BCL6, LMO2, and GCET1 in GC-DLBCL; and CD30, CD15, EBV, BOB1, OCT2, and CD79a in HL [15]. This evidence concerns the gene POU2AF1 and diffuse large B-cell lymphoma.