Leafs extract lowered blood sugar levels and improved the metabolism of diabetic rats through the regulation of glucose uptake in the liver and muscles by activating PKB/Akt and reestablishing the equilibrium of intracellular energy [134,135]. Aqueous extracts of leaves and seeds exhibited hypoglycemic effects [53,149,150]. Inhibition of α-amylase and α-glucosidase, hence lowering of post-prandial hyperglycemia [151]. This evidence concerns the gene AKT1 and Hyperglycemia.