Moreover, it has been demonstrated that falcarinol and falcarindiol polyacetylenes are able to inhibit ABCG2, the efflux protein also known as BCRP (breast cancer resistance protein) involved in breast cancer chemotherapy resistance, and mitochondrial aldehyde dehydrogenase (ALDH2) by covalently binding to these proteins [104]. This evidence concerns the gene ABCG2 and breast cancer.