Intestinal goblet cells are crucial for promoting intestinal defense against parasites, viruses, and bacteria thanks to secreting trefoil factor peptides (TFF), mucins, Fc-γ binding protein (Fcgbp), or resistin-like molecule β (RELMβ), which help to actively detect and respond to infections or improve the regeneration of the mucosa [24,28,29]. This evidence concerns the gene RETNLB and infection.