On the other hand, in PRAD, upregulation of the expression of glucosaminyl (N-acetyl) transferase 1 (GCNT1) leads to aberrant expression of SLex on MUC1, but whether this aberrant O-glycosylation is involved in prostate carcinogenesis has not been clearly stated [105]. The gene discussed is MUC1; the disease is prostate adenocarcinoma.