Additionally, we showed that ET conditions attenuated the IL-6 expression in co-cultured cells (4T1 or CT26 and MoET) compared to the IL-6 level measured in the co-culture of cancer cells with macrophages exposed previously to LPS once (i.e., for 4T1 and CT26, p < 0.001) (Figure 6A,C). The gene discussed is DDX53; the disease is cancer.