Given our observation of a reciprocal pattern of ACVR2A and ACVR2B protein expression between chemo-sensitive and chemo-resistant HL60 cells (Figure 2) and the increase in ACVR2A mRNA seen upon relapse of primary AML (Figure 5), it was of particular interest to test for correlation between mRNA expression levels and overall survival in the TGCA dataset. Here, ACVR2B is linked to acute myeloid leukemia.