No changes were observed in the levels of CD8+ T cells between groups (Figure 3B, left graph), although the expression of the degranulation marker CD107a reduced 1.4-fold (p = 0.0338) in CD8+ T cells from the CML On TKI individuals before vaccination (Figure 3B, right graph), although it increased 1.5-fold (p = 0.0014) after vaccination, in comparison to the healthy donors. The gene discussed is CD8A; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.